Dipotassium Glycyrrhizinate 65% 70% 72% | CAS: 68797-35-3

High-Purity Bio-Active Raw Material for Premium Anti-Stimulus, Sebum Regulation, and Skin Barrier Reconstruction Solutions

Understanding Dipotassium Glycyrrhizinate (CAS: 68797-35-3)

A dual-action botanical derivative designed for inflammatory pathway inhibition and sebum homeostasis.

Optimized Purity Tiers

Available in precise assays of 65%, 70%, and 72%. Higher purity configurations offer superior crystalline solubility, reducing precipitation risks in complex emulsion structures and stabilizing clear formulations.

Advanced Redness Mitigation

Dipotassium Glycyrrhizinate acts as a natural antagonist to the arachidonic acid cascade. It blocks downstream inflammatory media, including PGE2, effectively calming erythematous skin and reducing swelling.

Selective Sebum Control

Unlike aggressive astringents, it balances lipid production by modulating 5-alpha-reductase pathways within follicular cells, delivering a shine-free matte appearance without disrupting skin barrier lipids.

Physicochemical Specifications & Analytical Benchmarks

Verified laboratory standards for premium cosmetics and personal care formulations.

Parameter / Specification 65% Standard Grade 70% Premium Grade 72% Ultra-High Purity Grade
Appearance White to light yellow fine powder White to off-white crystalline powder Pure white crystalline powder
Assay (HPLC, dry basis) ≥ 65.0% ≥ 70.0% ≥ 72.0%
pH value (1% aq. solution) 5.0 – 7.0 5.5 – 7.5 5.8 – 6.8
Heavy Metals (as Pb) ≤ 10 ppm ≤ 5 ppm ≤ 2 ppm
Loss on Drying ≤ 8.0% ≤ 6.0% ≤ 5.0%
Application Focus Basic rinse-off, daily cleansers Leave-on skincare, targeted serums Sensitive skin clinical repair, ampoules

Global Regulatory Compliance & E-E-A-T Validation

Navigating compliance hurdles in the EU, US, and APAC markets with certified traceability.

International Ingress

Fully listed on the China IECIC (2021), approved under the EU Cosmetic Regulation (EC) No 1223/2009, and recognized as safe for OTC formulations by the US FDA. Full REACH registration documentation is accessible upon request.

Vertically Integrated Supply Chain

Direct sourcing from GMP-compliant factories in China allows for complete supply chain transparency. Our manufacturing partner, Suzhou Yuantairun Chemical Co., Ltd. (YuantaiRun), monitors production from initial extraction to final distribution.

Traceability Protocols

Every single batch undergoes stringent Quality Assurance testing, including HPLC mapping, heavy metal assays, and microbial checks. Certificates of Analysis (COA) and MSDS files are automatically provided with every shipment.

15+
Years in Raw Material Export
7000+
Cooperative Partners Globally
100%
GMP & ISO Audited Sites
24h
Global Logistics & Tech Support

Targeted Formulation Applications

Unlock the full synergistic potential of Dipotassium Glycyrrhizinate in diverse skin health formulations.

Sensitive Skin Care

Formulate soothing moisturizers and relief creams for reactive skin. Combine Dipotassium Glycyrrhizinate with D-Panthenol 98% to repair skin barrier function and minimize burning or tingling sensations.

Sulfate-Free Cleansers

Incorporate into gentle facial washes alongside amino acid surfactants, such as Sodium Cocoyl Glycinate 95%, to maintain lipid barrier integrity and prevent irritation during cleansing.

Scalp & Hair Therapeutics

Use in anti-dandruff and soothing scalp formulations. It helps calm itching and redness on the scalp when combined with mild surfactants like APG1214 Lauryl Glucoside, supporting hair follicle health.

Frequently Asked Questions

Expert technical insights regarding stability, solubility, and formulation dynamics.

Q1: How do the solubility properties of 65%, 70%, and 72% grades compare?
Higher purity grades (70% and 72%) feature a refined crystalline structure with fewer organic salts. This helps them dissolve quickly in water at room temperature, producing clear solutions without needing heat. Standard 65% grade is well-suited for rinse-off systems where high clarity is not critical.
Q2: What is the optimal pH range for formulating Dipotassium Glycyrrhizinate?
The ingredient is most stable within a pH range of 5.5 to 7.5. Falling below pH 4.5 can cause glycyrrhizic acid to precipitate, reducing the formula's effectiveness.
Q3: How does it pair with other active ingredients like Provitamin B5 (D-Panthenol)?
It works synergistically with cell-repair agents like D-Panthenol. While Dipotassium Glycyrrhizinate targets inflammation pathways (like PGE2 inhibition), D-Panthenol boosts cell turnover and skin barrier lipids, offering a comprehensive soothing effect.
Q4: Are there issues using it alongside high-electrolyte surfactant systems?
Dipotassium Glycyrrhizinate is an organic salt and may affect the viscosity of surfactant thickeners. Using it with non-ionic surfactants like APG1214 helps prevent formula separation.
Q5: Is it compliant with clean beauty and vegan standards?
Yes, our Dipotassium Glycyrrhizinate is derived from natural licorice roots through sustainable extraction methods. It contains no animal products and meets clean beauty guidelines globally.

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Partner with Suzhou Yuantairun Chemical Co., Ltd. for reliable supply chains, custom specifications, and international regulatory documentation support.

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