High-Quality Ethylhexylglycerin 99.5% Liquid

Premium Cosmetic Grade Preservative Booster, Skin Conditioning Agent & Deodorizer | CAS NO.: 70445-33-9

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Technical Monograph: Ethylhexylglycerin 99.5% (CAS 70445-33-9)

An exhaustive scientific study on molecular mechanisms, synergy with preservation systems, and formulation efficacy in clean beauty cosmetic science.

1. Introduction to high-purity Ethylhexylglycerin

Ethylhexylglycerin (IUPAC name: 3-[2-ethylhexyloxy]propane-1,2-diol) has emerged as an indispensable multifunctional cosmetic ingredient. At a purity level of 99.5% Min, this high-grade liquid serves as a high-efficiency preservative booster, an outstanding skin conditioning agent (emollient), and a targeted deodorizing active. As global clean beauty initiatives steer cosmetic chemists away from traditional formaldehyde donors, parabens, and highly scrutinized preservatives, EHG acts as a pivotal stabilizing tool.

Synthesized through the controlled condensation of glycerol with 2-ethylhexyl derivatives, high-grade Ethylhexylglycerin (EHG) is a clear, virtually colorless, and odorless liquid. Its amphiphilic molecular structure allows it to position itself at oil-water interfaces, modifying the surface tension of formulation systems and disrupting the cell walls of microbial pathogens. This physical disruption makes it a powerful booster, rendering microorganisms susceptible to main preservation compounds.

Property Parameter Technical Specifications (Cosmetic Grade 99.5%)
Chemical Formula C11H24O3
CAS Number 70445-33-9
Assay (Purity via GC) ≥ 99.5%
Appearance Clear, colorless, low-viscosity liquid
Refractive Index (20°C) 1.449 – 1.453
Density (20°C) 0.950 – 0.960 g/cm³

2. The Mechanism of Preservative Synergism

Ethylhexylglycerin is not classified as a preservative on chemical registries, yet its inclusion significantly lowers the Minimum Inhibitory Concentration (MIC) of conventional preservation systems. This occurs via cell membrane disruption: the hydrophobic tail of the EHG molecule inserts into the lipid bilayer of the microbial cell envelope. This destabilizes the membrane structural integrity and increases its permeability.

Consequently, secondary preservative agents like Phenoxyethanol, Benzyl Alcohol, or Caprylyl Glycol can penetrate the cellular wall and perform their bacteriostatic/fungicidal actions at lower concentrations. This synergy reduces formulation toxicity profiles and reduces the likelihood of localized contact dermatitis in consumers.

Formulation Spotlight: Synergy with Phenoxyethanol

Combining Phenoxyethanol (typically at 0.5% - 0.8%) with Ethylhexylglycerin 99.5% (at 0.1% - 0.2%) yields a broad-spectrum, globally compliant preservation system. This combination is highly effective against Gram-negative bacteria (such as Pseudomonas aeruginosa), Gram-positive bacteria (including Staphylococcus aureus), yeasts (such as Candida albicans), and molds (Aspergillus brasiliensis).

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3. Chinese Manufacturing Advantages for Ethylhexylglycerin 99.5%

In the global daily chemical supply chain, manufacturing partnerships with Chinese chemical plants offer significant competitive advantages. China's chemical industry operates within integrated industrial parks, which helps stabilize upstream feedstock markets (such as glycidyl ether and epoxidation chemicals) and guarantees reliable production volumes.

Suzhou Yuantairun Chemical utilizes advanced fractional vacuum distillation setups that refine Ethylhexylglycerin raw streams to an ultra-pure ≥99.5% specification. This process keeps residual free amines, heavy metals, and moisture to trace levels, mitigating the color shift or offensive amine odor issues that often plague lower-purity variants.

Our production processes comply with strict environment-protection regulations, and we use modern wastewater treatment systems and energy-efficient practices. Standardizing production batches according to ISO 9001 and ISO 22716 guidelines ensures that global cosmetic buyers receive product of consistent quality, batch after batch.

4. Global Buying Criteria and Procurement Dynamics

For international procurement teams representing major cosmetic brands, sourcing Ethylhexylglycerin goes beyond cost optimization. It requires meeting strict regulatory, safety, and performance standards:

  • Odor Profile: EHG is commonly used in unscented or fragrance-free formulations. This requires a completely neutral-smelling raw material that will not alter the fragrance profile of the final product.
  • REACH Compliance: European market access requires full registration and active compliance dossiers.
  • Impurities Control: Minimizing residual reactants, specifically 2-ethylhexanol and free glycerol, is crucial to prevent skin sensitization.
  • Stable Delivery & Supply Chain Security: Implementing Just-in-Time (JIT) logistics helps global formulators maintain lean inventories without risking production interruptions.
2010
Founded In
7000+
Cooperative Partners
99.5%
EHG Pure Assay
100%
Global Regulatory Compliance

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Technical Q&A / FAQ

Scientific answers regarding formulation chemistry, stability, compatibility, and global standards for Ethylhexylglycerin (CAS 70445-33-9).

What are the primary functional benefits of Ethylhexylglycerin 99.5%?
Ethylhexylglycerin is a multifunctional additive. It is mainly used as a preservative booster that increases the performance of preservatives like Phenoxyethanol. Additionally, it serves as a skin-friendly emollient (conditioning agent) to improve formulation texture and acts as a deodorizing agent by inhibiting odor-causing bacteria.
How does Ethylhexylglycerin act as a preservative booster?
EHG reduces the surface tension of water and interacts with microbial cell membranes. By accumulating at the cell envelope of micro-organisms, it disrupts membrane structural integrity. This allows co-formulated preservatives to penetrate the microbial cell wall more easily, lowering the required dosage of traditional preservatives.
Why is a 99.5% purity specification critical for cosmetic formulations?
Lower-purity EHG can contain residual reactants such as 2-ethylhexanol. These impurities can introduce strong chemical odors, cause discoloration, or lead to skin irritation in finished formulations. A 99.5% purity specification ensures stability and compatibility with fragrance-free and sensitive skin products.
What is the recommended dosage range for EHG in skincare?
For most cosmetic emulsions, body washes, and leave-on creams, the recommended dosage is between 0.1% and 0.5% by weight. Using it alongside preservatives like Phenoxyethanol at 0.5% - 0.9% typically provides robust, broad-spectrum microbial protection.
What are the pH limits and temperature stability of Ethylhexylglycerin?
Ethylhexylglycerin is structurally stable. It is effective across a wide pH range (2.0 to 12.0) and can withstand manufacturing temperatures up to 80°C, allowing it to be added to the oil phase before emulsification.
How does EHG support deodorizing actions in personal care products?
EHG selectively targets and inhibits the growth of Gram-positive bacteria, such as Corynebacterium xerosis, which are responsible for body odor. It achieves this without significantly disrupting the natural, protective skin microbiome.
Is Ethylhexylglycerin safe for infant care and sensitive skin?
Yes. Extensive toxicological reviews show that at recommended cosmetic use concentrations (up to 1.0%), EHG is non-irritating and non-sensitizing, making it suitable for baby care and sensitive skin formulations.
What are the recommended packaging and storage guidelines for EHG?
EHG should be stored in tightly sealed original containers, away from direct sunlight, moisture, and extreme temperatures. It is recommended to store it in a cool, dry, well-ventilated area between 5°C and 30°C.

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